COMPOSITION  
Each film coated tablet contains:
Diclofenac Potassium B.P. 50 mg

Arachidonic Acid in presence of Cyclo-Oxygenase it tranformed to Prostaglandins which causes inflammation and leads to pyrexia and pain. There are 2 types of Cyclo-Oxygenase (COX) enzymes, COX-1 & COX-2. COX-1 is a friendly enzyme and COX-2 is a destructive enzyme which produce Prostaglandins which are harmful for the body.Diclofenac inhibits COX-2 rather than COX-1 & hence it is safe.
It is well absorbed orally, 99% protein bound, distributed throughout the body fluids, metabolized in liver and excreted in both urine and bile. The plasma t1/2 is nearly 2 hours.

Rationale of using Diclofenac 'Potassium'

• Diclofenac potassium is fast acting as compared to Diclofenac sodium due to its quicker dissolution and absorption. Its Peak plasma concentration is reached in approx. 45 minutes as compared to 2 hours of that of enteric coated sodium salt.

• The faster onset of action onset of action makes diclofenac potassium particularly suitable for acute inflammatory conditions.

• Ideally suited for hypertensive patients.

• Ideally suited for patients on diuretic therapy.

INDICATIONS OF DOLOCIDE K

• Post operative & Post traumatic inflammation

• Muscular & Skeletal Pain

• Painful Inflammatory conditions

• Stiff Neck

• Spondylitis

• Low Back Pain

• Osteoarthritis

• Rheumatoid Arthritis

DOSAGE
1 tablet 3 times daily.

CONTRAINDICATIONS
GI bleeding, Active peptic ulcer, NSAID induced allergic asthma.