COMPOSITION  
Each capsule contains:
Amoxycillin Trihydrate I.P. equivalent to Amoxycillin 250 mg
Cloxacillin Sodium I.P.equivalent to Cloxacillin 250 mg
Lactic Acid Bacillus 60 million spores
 


Amoxycillin inhibits the synthesis of the bacterial cell wall. Thus the multiplying cells can not make their normal cell wall and they ultimately die.
Cloxacillin - It has an isoxazolyl side chain that protect the b-lactam ring from attack by penicillinase and is highly penicillinase as well as acid resistant. It does not get inactivated by the bacterial enzymes.
Lactic Acid bacillus spores - Lactobacilli or Lactic acid bacillus are friendly bacteria which form the lining of intestinal mucosa. These friendly bacteria are generally killed by antibiotics leading to diarrhoea & gastric upsets. Thus, supplementation of Lactobacilli spores with antibiotics prevents diarrhoea & gastric upsets.
INDICATIONS
Respiratory Tract Infections
Tonsillar abscess, otitis media, suppurative sinus infection, acute chronic bronchitis, bronchiectasis, bronchopneumonia, pleurisy, empyema, lung abscess, emphysema, bronchiolitis.

Urinary Tract  Infections
Acute and chronic pyelonephritis, cystitis, urethritis.

Skin  & Soft  Tissue Infections
Recurrent boils, carbuncles, impetigo, cellulitis and other infected dermatoses.

Bone Infections
Osteomyelitis and septic arthritis

Serious Infections
Septicemia, bacterial endocarditis, brain abscess and bacterial meningitis
DOSAGE & ADMINISTRATION
The dosage differs depending on the type, site and severity of infections. It is usually given as one capsules three to four times daily.
In impaired renal function the dosage should be modified in patients with severe renal impairment, by increasing the intervals between doses. With a creatinine clearance between 10 and 50 ml/min the dosing interval can be up to 12 hours. If the clearance is less than 10 ml/min the interval can be 16 hours.
CONTRAINDICATIONS
History of allergic reaction to any of the penicillins.
 
 Learn More . . .
 Composition 
 Indications
 Dosage
 Contraindications
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